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KMID : 1150720180070040322
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Integrative Medicine Research
2018 Volume.7 No. 4 p.322 ~ p.327
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Tualang honey adjunct with anastrozole improve parenchyma enhancement of breast tissue in breast cancer patients: A randomized controlled trial
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Hizan Nik Shah
Hassan Nor Hasnina Mohd
Haron Juhara
Abubakar Murtala Bello
Mahdi Nik Munirah Nik
Gan Siew Hua
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Abstract
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Background: To investigate whether the combination of anastrozole and Tualang honey (T honey) influences background parenchymal enhancement (BPE) in breast magnetic resonance imaging (MRI) of postmenopausal women with breast cancer.
Methods: A total of 30 patients were recruited and randomly divided into control (anastrozole 1?mg daily) and intervention (anastrozole 1?mg?+?T honey 20?g daily). The BPE of the contralateral breast before and six months following treatment was compared using the sign test.
Results: There was a decrease in BPE in 10% of the women (p?=?0.317) who received only anastrozole, which resulted in a change of BPE category from moderate to mild. However, the combination of anastrozole and T honey evoked a decrease in BPE in 42% of the patients (p?=?0.034).
Conclusions: The combination of T honey and anastrozole maybe more efficacious than anastrozole alone in decreasing breast BPE in breast cancer patients. These findings support the medicinal value of T honey as an adjuvant treatment to anastrozole.
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KEYWORD
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Anastrozole, Breast cancer, Honey, MRI
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